01 - Heat a large skillet over medium-high heat. Add the ground beef, salt, pepper, smoked paprika, and garlic powder. Break up the meat with a spatula and cook, stirring occasionally, until browned and cooked through, approximately 7–8 minutes. Drain excess fat if necessary.
02 - In a small bowl, whisk together the mayonnaise, ketchup, yellow mustard, dill pickle relish, apple cider vinegar, smoked paprika, and a pinch of salt and pepper until smooth and well combined. Set aside until ready to serve.
03 - Divide the chopped romaine lettuce evenly among four large serving bowls. Arrange equal portions of the cooked ground beef, cherry tomatoes, shredded cheddar cheese, sliced red onion, pickle slices, and diced avocado over the lettuce in each bowl.
04 - Drizzle the prepared burger sauce generously over each bowl. Serve immediately while the beef is still warm.